INDICATION
ALOXI® is indicated for:
- the prevention of acute nausea and vomiting associated with initial and repeat courses of moderately and highly emetogenic cancer chemotherapy, and
- the prevention of delayed nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy.
CONTRAINDICATIONS
ALOXI is contraindicated in patients known to have hypersensitivity to the drug or any of its components.
ADVERSE REACTIONS
The most commonly reported adverse reactions were similar to those seen with other 5-HT3 receptor antagonists.
- Headache (9%)
- Constipation (5%)
GENERAL PRECAUTIONS
ALOXI should be administered with caution in patients who have or may develop prolongation of cardiac conduction intervals, particularly QTc.
(See full Precautions section of full Prescribing Information).