ALOXI Support Program

Not feeling nauseous can help you during chemotherapy, so can the resources listed here that you can download and print.

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Tips to manage CINV

Help prevent and manage chemotherapy-induced nausea and vomiting (CINV) with these diet and lifestyle tips.

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If you are a healthcare professional outside of the U.S., please visit Aloxi.net.

Perception vs Reality

Question: Is it important for your treatment team to know you are experiencing nausea and vomiting?

Answer: It is in your best interest to tell them if you feel nauseous right after chemotherapy or even days later. A study showed that many healthcare providers may not be aware of how often their patients become nauseous or vomit after chemotherapy. But that does not mean their patients are not getting sick.

Physician-predicted and observed rates of chemotherapy-induced nausea and vomiting (CINV)during the acute phase (0-24 hours after treatment) and the delayed phase (24 to 120 hours after treatment) can be quite different from what patients actually experience (Figure 1). Given what we know about how much patients dread CINV, this is cause for concern.

(Figure 1) Predicted nausea and vomiting compared to actual patient experience*1

*These patients received moderately emetogenic chemotherapy, or chemotherapy that is moderately likely to cause nausea and vomiting.

Question: What is the best way to close the perception/reality gap about CINV?

Answer: First, patients need to be aware of their risk for CINV. Discussing risk factors with your healthcare provider may help you find ways to prevent symptoms from occurring in the first place.

Second, if symptoms do occur, patients should bring it to the attention of their treatment team. It may help to keep a daily calendar or checklist of symptoms to discuss during appointments. That way, your treatment team will know what you are dealing with and can create a treatment plan accordingly.

Third, patients need to know that they may not have to feel nauseous from chemotherapy. They can make diet and lifestyle changes and talk to their healthcare team about antinausea mediations that can help prevent nausea and vomiting on the day of chemotherapy and even days after.

Whether it's your first experience with chemotherapy or you've been through it before, talking with your healthcare provider about preventing CINV is important.

Reference:

1. Grunberg SM, Deuson RR, Mavros P, et al. Incidence of chemotherapy-induced nausea and emesis after modern antiemetics. Cancer. 2004;100:2261-2268.

Indication

ALOXI is used in adults to help prevent the nausea and vomiting that can happen on the day of treatment with certain chemotherapies or occur days later following chemotherapies moderately likely to cause nausea and vomiting.

Important Safety Information

  • Tell your healthcare professional if you are taking other medications or if you are pregnant or breastfeeding
  • The most common side effects of ALOXI® for the prevention of CINV are headache and constipation

For more information about ALOXI talk to your doctor or see Full Prescribing Information.

ALOXI is available by prescription only.

The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient.

This site is intended for residents of the United States only. The products discussed herein may have different product labeling in different countries.