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Acute Nausea & Vomiting

The first phase of chemotherapy-induced nausea and vomiting (CINV) is referred to as acute CINV.¹

Acute CINV occurs within the first 24 hours following chemotherapy administration, with the highest risk period occurring during the first 4 hours of treatment.² Many factors determine how nausea occurs and how severe it will be. These factors include drug, dose, schedule of administration and route.³

In addition, acute CINV is more likely to occur in cancer patients who have experienced nausea and vomiting after previous chemotherapy sessions, in females, in patients who drink little or no alcohol, and in younger patients.³

References

Bender CM, McDaniel RW, Murphy-Ende K, et al. Chemotherapy-induced nausea and vomiting. Clin J Oncol Nurs 2002; 6:94-102.
Gralla R. Management of nausea and vomiting. Cancer Management: A multidisciplinary approach, 2001.
National Institutes of Health. National Cancer Institute Web site. Nausea and Vomiting (PDQ).
http://www.nci.nih.gov/cancerinfo/pdq/supportivecare/nausea/patient/#Section_13

During initial and repeat courses of chemotherapy, ALOXI helps prevent and control nausea and vomiting the day following chemotherapy that is highly likely to cause nausea and vomiting, and for up to 5 days following chemotherapy that is likely to cause nausea and vomiting. The most frequent side effects of ALOXI include headache and constipation. If you have or may develop significant heart rhythm changes, talk with your healthcare professional before receiving ALOXI.

ALOXI is available by prescription only. Please see the important product information for ALOXI for more information.

This site does not contain everything that is known about ALOXI. If you would like to know more, talk to your healthcare professional.