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Delayed Nausea & Vomiting

The second phase of chemotherapy-induced nausea and vomiting (CINV) is referred to as delayed CINV.¹

Delayed CINV occurs more than 24 hours after chemotherapy is administered and may persist for several days.² There have been some indications that delayed CINV may happen as early as 16 hours after chemotherapy is initiated.²

This second phase of CINV is more likely to occur in patients receiving high-dose chemotherapy regimens, in patients who have experienced acute nausea and vomiting with chemotherapy, in females, in patients who drink little or no alcohol, and in young patients.³

Antiemetic therapy may be given alone or in combination to patients who are receiving chemotherapy.³

References

Bender CM, McDaniel RW, Murphy-Ende K, et al. Chemotherapy-induced nausea and vomiting. Clin J Oncol Nurs 2002; 6:94-102.
Gralla R. Management of nausea and vomiting. Cancer Management: A multidisciplinary approach, 2001.
National Institutes of Health. National Cancer Institute Web site. Nausea and Vomiting (PDQ).
http://www.nci.nih.gov/cancerinfo/pdq/supportivecare/nausea/patient/#Section_13

During initial and repeat courses of chemotherapy, ALOXI helps prevent and control nausea and vomiting the day following chemotherapy that is highly likely to cause nausea and vomiting, and for up to 5 days following chemotherapy that is likely to cause nausea and vomiting. The most frequent side effects of ALOXI include headache and constipation. If you have or may develop significant heart rhythm changes, talk with your healthcare professional before receiving ALOXI.

ALOXI is available by prescription only. Please see the important product information for ALOXI for more information.

This site does not contain everything that is known about ALOXI. If you would like to know more, talk to your healthcare professional.