What is chemotherapy-induced nausea and vomiting?
Chemotherapy is a type of cancer treatment. The goal of chemotherapy is to kill harmful cancer cells. Chemotherapy affects both cancer cells and normal cells.
Nausea and vomiting can be a side effect of chemotherapy. Nausea can lead to vomiting, which is throwing up the contents of your stomach. Nausea and vomiting due to your chemotherapy treatment is called chemotherapy-induced nausea and vomiting, or CINV.
Nausea is the feeling you have when you are going to throw up
Vomiting (emesis) is the act of throwing up what is in your stomach
Some chemotherapy treatments may cause nausea and vomiting that can last for up to 5 days.
Will my chemotherapy cause nausea and vomiting?
Not all chemotherapy causes nausea and vomiting. Nausea and vomiting can start right after you receive chemotherapy or sometimes days later. You may not get nauseated or vomit during treatment. You may experience nausea or vomiting, or both. Your healthcare team can tell you if your chemotherapy is likely to cause nausea and vomiting.
How "emetic" a medicine is refers to how likely it is to cause vomiting.
Chemotherapy that is highly emetic means that there is a high risk it will cause nausea and vomiting
Chemotherapy that is moderately emetic means that there is a moderate risk it will cause nausea and vomiting
Important Safety Information
ALOXI® can cause allergic reactions that can be serious. Tell your doctor or nurse right away if you have any of these following symptoms of a serious allergic reaction: hives, swelling of the face, trouble breathing and chest pain
The most common side effects of ALOXI in adults are headache and constipation
Tell your doctor or nurse if you are taking other medications or if you are pregnant or breastfeeding or plan to become pregnant or breastfeed
Indication in Adults
ALOXI injection 0.25 mg/5 mL is used in adults to help prevent nausea and vomiting on the day of chemotherapy that is highly likely to cause nausea and vomiting, and up to 5 days following chemotherapy that is moderately likely to cause nausea and vomiting.
Indication in Pediatrics
ALOXI injection 20 mcg/kg (max 1.5 mg) is used in children 1 month old to less than 17 years of age to help prevent nausea and vomiting on the day of chemotherapy that is moderately or highly likely to cause nausea and vomiting.
For more information about ALOXI, talk to your doctor or see Full Prescribing Information.
ALOXI is available by prescription only.