About Chemotherapy-Induced Nausea
and Vomiting

If you are starting chemotherapy you are probably experiencing many feelings, both emotional and physical. Unfortunately, chemotherapy and vomiting might be among them.

Chemotherapy is administered in order to hopefully eliminate cancer cells in the body. Very often, healthy cells may be damaged or destroyed as well. The body recognizes that chemotherapy is a toxin and may send a message to the brain that a toxin is present. One of the most common triggers of nausea or vomiting from chemotherapy is the release of serotonin from your body. Serotonin may attach to receptors known as 5-hydroxytryptamine-3 (5-HT3) sending off signals to the brain. When the signals reach the brain, nausea and vomiting known as chemotherapy-induced nausea and vomiting, or CINV may result.

  • Nausea is a subjective condition, marked by an unpleasant sensation in the throat and stomach. Nausea may or may not result in vomiting
  • Vomiting is the expulsion of stomach contents through the mouth

CINV may be prevented

The good news is that you can take measures to keep CINV at bay. There are medicines to help keep you from feeling sick after receiving chemotherapy.

Indication

  • ALOXI injection is used in adults to help prevent nausea and vomiting on the day of chemotherapy that is highly likely to cause nausea and vomiting, and up to 5 days following chemotherapy that is moderately likely to cause nausea and vomiting

Important Safety Information

  • Tell your health care professional if you are taking other medications or if you are pregnant or breastfeeding
  • The most common side effects of ALOXI® for the prevention of CINV are headache and constipation

Please read the Full Product Information and discuss it with your doctor or health care professional.

ALOXI is available by prescription only.


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit http://www.FDA.gov/medwatch or call 1-800-FDA-1088.


You are Now Leaving Aloxi.com

Eisai Inc. does not review the information contained on the following website for content, accuracy or completeness. Use of and access to the information is subject to the terms, limitations and conditions set by the website producer. Eisai Inc. makes no claims about the accuracy or any other aspect of the information contained on this website, nor does Eisai Inc. endorse this website.



Health Care Professionals

This information is intended for U.S. Health Care Professionals. Click the "CONTINUE" button below to verify that you area U.S. Health Care Professional, or the "CANCEL" button to return to the previous page.