ALOXI® (Ah-lock-see)
Palonosetron HCl injection
Your role is critical in your patients' chemotherapy experience. The marketers of ALOXI are here to support you. Below is important patient information about ALOXI.
WHAT IS ALOXI USED FOR?
ALOXI is used to prevent nausea and vomiting that may happen:
- soon after taking certain anti-cancer medicines
- later after taking certain anti-cancer medicines
WHO SHOULD NOT TAKE ALOXI?
Do not take ALOXI if you are allergic to any of the ingredients in ALOXI.
The active ingredient is palonosetron hydrochloride. See the end of this section
for a complete list of ingredients in ALOXI.
ALOXI has not been studied in children under 18 years of age.
WHAT SHOULD I TELL MY DOCTOR BEFORE USING ALOXI?
Tell your doctor about all of your medical conditions, including if you:
- have low potassium in your blood
- have low magnesium in your blood
- are pregnant. It is not known if ALOXI may harm your unborn baby. You and
your doctor should decide if ALOXI is right for you.
- are breastfeeding. It is not known if ALOXI passes into your milk and if
it can harm your baby. You should choose to either take ALOXI or breastfeed, but
not both.
Tell your doctor about all of the medicines you take including prescription and nonprescription
medicines, vitamins and herbal supplements. ALOXI should be given with caution
in patients who may be taking other medicines that have caused, or may cause, severe
heart beat changes.
Especially, tell your doctor if you take:
- “water pills” (diuretics)
- medicine to control your heartbeat (anti-arrythmics)
- anthracycline (an anti-cancer medicine)
HOW SHOULD I USE ALOXI?
ALOXI is given in your vein by IV (intraveneous) injection. It is only given to
you by a healthcare provider in a hospital or clinic. ALOXI is usually injected
into your vein about 30 minutes before you get your anti-cancer medicine (chemotherapy).
WHAT ARE THE POSSIBLE SIDE EFFECTS OF ALOXI?
ALOXI should be given with caution in patients who have or may develop severe heart
beat changes from QT prolongation. This can happen in people who have certain heart
or other medical problems or who take certain medicines.
The most common side effects of ALOXI are headache and constipation. Diarrhea
and dizziness have also been observed.
These are not all the side effects from ALOXI. For more information ask your doctor
or pharmacist.
GENERAL INFORMATION ABOUT ALOXI
Medicines are sometimes prescribed for conditions other than those listed in patient
information leaflets. ALOXI was prescribed for your medical condition.
This section summarizes the most important information about ALOXI. If you would
like more information, talk with your doctor. You can ask your doctor or pharmacist
for information about ALOXI that is written for health professionals.
WHAT ARE THE INGREDIENTS IN ALOXI?
Active ingredient: palonosetron hydrochloride
Inactive ingredients: mannitol, disodium edetate, and citrate buffer in water