How does ALOXI® work?
What causes chemotherapy-induced nausea and vomiting?
Chemotherapy causes chemical signals to travel to a part of the brain called the "vomiting center." These signals may make you feel nauseated or cause you to vomit. This is known as chemotherapy-induced nausea and vomiting.
How does ALOXI help prevent chemotherapy-induced nausea and vomiting?
ALOXI is thought to work by blocking some of these signals in the brain's vomiting center. This helps prevent nausea and vomiting due to chemotherapy.
Important Safety Information
ALOXI® can cause allergic reactions that can be serious. Tell your doctor or nurse right away if you have any of these following symptoms of a serious allergic reaction: hives, swelling of the face, trouble breathing and chest pain
The most common side effects of ALOXI in adults are headache and constipation
Tell your doctor or nurse if you are taking other medications or if you are pregnant or breastfeeding or plan to become pregnant or breastfeed
Indication in Adults
ALOXI injection 0.25 mg/5 mL is used in adults to help prevent nausea and vomiting on the day of chemotherapy that is highly likely to cause nausea and vomiting, and up to 5 days following chemotherapy that is moderately likely to cause nausea and vomiting.
Indication in Pediatrics
ALOXI injection 20 mcg/kg (max 1.5 mg) is used in children 1 month old to less than 17 years of age to help prevent nausea and vomiting on the day of chemotherapy that is moderately or highly likely to cause nausea and vomiting.
For more information about ALOXI, talk to your doctor or see Full Prescribing Information.
ALOXI is available by prescription only.