Risk for chemotherapy-induced nausea and vomiting (CINV)
Your oncology team will create a treatment plan specifically for you. As part of this plan, chemotherapy may be administered to help you fight your cancer. Certain types of chemotherapy can cause people to feel sick. Feeling sick often includes nausea and vomiting.
Approximately 70% to 80% of patients receiving chemotherapy experience CINV.
About 7 or 8 out of 10 people receiving chemo may experience CINV without preventive measures.
Patients experiencing CINV
Patients not experiencing CINV
Not all chemotherapy causes the same level of CINV. Some types of chemotherapy have a greater risk of making you feel sick. This is called emetogenic (eh-meh-tow-JEH-nik) potential.
Chemotherapy that is highly emetogenic, or that has a high emetic risk, is very likely to cause nausea and vomiting (90% or more of the time) if no preventive measures are taken.
Chemotherapy that is likely to cause nausea and vomiting is called moderately emetogenic or is said to have moderate emetic risk. Chemotherapy that is moderately emetogenic, or that has a moderate emetic risk, is likely to cause nausea and vomiting 30% to 90% of the time if no preventive measures are taken.
Your healthcare professional can tell you if you will receive highly or moderately emetogenic chemotherapy.
Learn about how to decrease your chances of experiencing CINV.
Download our symptom tracker and share your results with your doctor or nurse.
Indication in Adults
ALOXI® injection 0.25 mg/5 mL is used in adults to help prevent nausea and vomiting on the day of chemotherapy that is highly likely to cause nausea and vomiting, and up to 5 days following chemotherapy that is moderately likely to cause nausea and vomiting.
Indication in Pediatrics
ALOXI injection 20 mcg/kg (max 1.5 mg) is used in children 1 month old to less than 17 years of age to help prevent nausea and vomiting on the day of chemotherapy that is moderately or highly likely to cause nausea and vomiting.
Important Safety Information
ALOXI can cause allergic reactions that can be serious. Tell your doctor or nurse right away if you have any of these following symptoms of a serious allergic reaction: hives, swelling of the face, trouble breathing and chest pain
The most common side effects of ALOXI in adults are headache and constipation
Tell your doctor or nurse if you are taking other medications or if you are pregnant or breastfeeding or plan to become pregnant or breastfeed
For more information about ALOXI, talk to your doctor or see full Prescribing Information.
ALOXI is available by prescription only.